When Preparing Your Application • Read the instructions • Never assume that reviewers “will know what you mean” • Refer to the literature thoroughly • State rationale of proposed investigation • Include well-designed tables and figures • Present an organized, lucid write-up • Remember to address human subjects, vertebrate animals, potential biohazards; these could affect your score • Obtain pre-review from faculty at your institution NIH Grant Writing Tips: http://grants.nih.gov/grants/grant_tips.htm
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NIH Expedited Reporting • Requirements for reporting vary by institute Institute NCCAM: NCI: NEI: NHLBI: NIA: NIAID: NIAMS: NICHD: NIDA: NIDCR: NIDDK: NIMH: NINDS: Data and Safety Monitoring Policies http://nccam.nih.gov/research/policies/datasafety/ http://deainfo.nci.nih.gov/grantspolicies/datasafety.htm http://www.nci.nih.gov/clinical_trials/conducting/ http://www.nei.nih.gov/funding/policy/policy6.htm http://www.nhlbi.nih.gov/funding/policies/dsmb_est.htm http://rover2.nhlbi.nih.gov/funding/policies/dsm-12.htm http://rover2.nhlbi.nih.gov/funding/policies/dataqual.htm http://www.nhlbi.nih.gov/funding/policies/dsmb_othr.htm http://www.nia.nih.gov/funding/policy/humint.htm http://www.niaid.nih.gov/ncn/pdf/clinterm.pdf http://www.niams.nih.gov/rtac/clinical/dsmb3.html http://www.niams.nih.gov/rtac/funding/grants/datasafe.htm http://www.nichd.nih.gov/funding/datasafety.htm http://www.nida.nih.gov/Funding/DSMBSOP.html http://www.nidcr.nih.gov/research/ctp/data_safety_monitoring_boards.pdf http://www.niddk.nih.gov/patient/patient.htm#policy http://www.nimh.nih.gov/research/safetymonitoring.cfm http://www.ninds.nih.gov/funding/ninds_patient_safety_guidelines.htm
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createconfigs script in src/mpp-mpred-3.2.0/p95/mu11 #!/bin/bash for g in .1 .2 .4 .7 .9 do sed -i -e "s/dMNsdsThr=[^ ]*/dMNsdsThr=$g/" t.config for h in .1 .2 .4 .7 .9 do sed -i -e "s/dMNsdsExp=[^ ]*/dMNsdsExp=$h/" t.config cp t.config configs/a$g$h.config done done creates in src.mpp-mpred-3.2.0/p95/mu11/configs: -rw-r--r-- 1 perrizo faculty 7441 Nov 3 10:11 a.1.1.config -rw-r--r-- 1 perrizo faculty 7441 Nov 3 10:11 a.1.2.config -rw-r--r-- 1 perrizo faculty 7441 Nov 3 10:11 a.1.4.config -rw-r--r-- 1 perrizo faculty 7441 Nov 3 10:11 a.1.7.config -rw-r--r-- 1 perrizo faculty 7441 Nov 3 10:11 a.1.9.config -rw-r--r-- 1 perrizo faculty 7441 Nov 3 10:11 a.2.1.config -rw-r--r-- 1 perrizo faculty 7441 Nov 3 10:11 a.2.2.config -rw-r--r-- 1 perrizo faculty 7441 Nov 3 10:11 a.2.4.config -rw-r--r-- 1 perrizo faculty 7441 Nov 3 10:11 a.2.7.config -rw-r--r-- 1 perrizo faculty 7441 Nov 3 10:11 a.2.9.config -rw-r--r-- 1 perrizo faculty 7441 Nov 3 10:12 a.4.1.config -rw-r--r-- 1 perrizo faculty 7441 Nov 3 10:12 a.4.2.config -rw-r--r-- 1 perrizo faculty 7441 Nov 3 10:12 a.4.4.config -rw-r--r-- 1 perrizo faculty 7441 Nov 3 10:12 a.4.7.config -rw-r--r-- 1 perrizo faculty 7441 Nov 3 10:12 a.4.9.config -rw-r--r-- 1 perrizo faculty 7441 Nov 3 10:12 a.7.1.config -rw-r--r-- 1 perrizo faculty 7441 Nov 3 10:12 a.7.2.config -rw-r--r-- 1 perrizo faculty 7441 Nov 3 10:12 a.7.4.config -rw-r--r-- 1 perrizo faculty 7441 Nov 3 10:12 a.7.7.config -rw-r--r-- 1 perrizo faculty 7441 Nov 3 10:12 a.7.9.config -rw-r--r-- 1 perrizo faculty 7441 Nov 3 10:12 a.9.1.config -rw-r--r-- 1 perrizo faculty 7441 Nov 3 10:12 a.9.2.config -rw-r--r-- 1 perrizo faculty 7441 Nov 3 10:12 a.9.4.config -rw-r--r-- 1 perrizo faculty 7441 Nov 3 10:12 a.9.7.config -rw-r--r-- 1 perrizo faculty 7441 Nov 3 10:12 a.9.9.config submit in src/mpp-mpred-3.2.0 produces here #!/bin/bash for g in .1 .2 .4 .7 .9 do for h in .1 .2 .4 .7 .9 do ./mpp-submit -S -i Data/p95test.txt -c p95/mu11/configs a$g$h.out -t .05 -d ./p95/mu11 done done -rw-r--r-- 1 perrizo faculty 3626 Nov 3 10:15 a.1.1.out -rw-r--r-- 1 perrizo faculty 3626 Nov 3 10:15 a.1.2.out -rw-r--r-- 1 perrizo faculty 3626 Nov 3 10:15 a.1.4.out -rw-r--r-- 1 perrizo faculty 3626 Nov 3 10:15 a.1.7.out -rw-r--r-- 1 perrizo faculty 3625 Nov 3 10:15 a.1.9.out -rw-r--r-- 1 perrizo faculty 3626 Nov 3 10:15 a.2.1.out -rw-r--r-- 1 perrizo faculty 3626 Nov 3 10:15 a.2.2.out -rw-r--r-- 1 perrizo faculty 3626 Nov 3 10:16 a.2.4.out -rw-r--r-- 1 perrizo faculty 3626 Nov 3 10:16 a.2.7.out -rw-r--r-- 1 perrizo faculty 3626 Nov 3 10:16 a.2.9.out -rw-r--r-- 1 perrizo faculty 3626 Nov 3 10:16 a.4.1.out -rw-r--r-- 1 perrizo faculty 3625 Nov 3 10:16 a.4.2.out -rw-r--r-- 1 perrizo faculty 3626 Nov 3 10:16 a.4.4.out -rw-r--r-- 1 perrizo faculty 3626 Nov 3 10:16 a.4.7.out -rw-r--r-- 1 perrizo faculty 3626 Nov 3 10:17 a.4.9.out -rw-r--r-- 1 perrizo faculty 3626 Nov 3 10:17 a.7.1.out -rw-r--r-- 1 perrizo faculty 3625 Nov 3 10:17 a.7.2.out -rw-r--r-- 1 perrizo faculty 3626 Nov 3 10:17 a.7.4.out -rw-r--r-- 1 perrizo faculty 3626 Nov 3 10:17 a.7.7.out -rw-r--r-- 1 perrizo faculty 3626 Nov 3 10:17 a.7.9.out -rw-r--r-- 1 perrizo faculty 3626 Nov 3 10:17 a.9.1.out -rw-r--r-- 1 perrizo faculty 3626 Nov 3 10:18 a.9.2.out -rw-r--r-- 1 perrizo faculty 3626 Nov 3 10:18 a.9.4.out -rw-r--r-- 1 perrizo faculty 3625 Nov 3 10:18 a.9.7.out -rw-r--r-- 1 perrizo faculty 3626 Nov 3 10:18 a.9.9.out which I then copy to src/mpp-mpred-3.2.0/dotouts.
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When Preparing an Application  Read instructions  Never assume that reviewers “will know what you mean”  Refer to literature thoroughly  State rationale of proposed investigation  Include well-designed tables and figures  Present an organized, lucid write-up  Obtain pre-review from faculty at your institution
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Not All 20 Point Fonts Are Equal 20  A - Can You Read B - Can You Read C - Can You Read D - Can You Read E - Can You Read F - Can You Read G - Can You Read H - Can You Read I - Can You Read 16  J - Can You Read K - Can You Read L - Can You Read M - Can You Read N - Can You Read O - Can You Read P - Can You Read Q - Can You Read R - Can You Read 14  J - Can You Read K - Can You Read L - Can You Read M - Can You Read O - Can You Read P - Can You Read Q - Can You Read R - Can You Read 12  J - Can You Read K - Can You Read L - Can You Read M - Can You Read N - Can You Read O - Can You Read P - Can You Read Q - Can You Read R - Can You Read My Students Tell Me That They Like The Readability Of Ariel Font I never use fonts smaller than 20 point for lecture.
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RESOURCE WEB LINKS  Office of Extramural Research Grants Home Page: http://grants.nih.gov/grants/oer.htm  NIH Grants Policy Statement (12/03): http://grants.nih.gov/grants/policy/nihgps_2003/index.htm  NIH Guide: http://grants.nih.gov/grants/guide/index.html  PHS 398 Application (form pgs are PDF-fillable): http://grants1.nih.gov/grants/funding/phs398/phs398.html  PHS2590 Progress Report (form pgs are PDF-fillable): http://grants.nih.gov/grants/funding/2590/2590.htm  Handy Reference: Activity Code, Organization Codes and Definitions Used In Extramural Programs: http://grants.nih.gov/grants/funding/ac.pdf 77
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RESOURCE WEB LINKS  Office of Extramural Research Grants Home Page: http://grants.nih.gov/grants/oer.htm  NIH Grants Policy Statement (12/03): http://grants.nih.gov/grants/policy/nihgps_2003/index.htm  NIH Guide: http://grants.nih.gov/grants/guide/index.html  PHS 398 Application (form pgs are PDF-fillable): http://grants1.nih.gov/grants/funding/phs398/phs398.html  PHS2590 Progress Report (form pgs are PDF-fillable): http://grants.nih.gov/grants/funding/2590/2590.htm  Handy Reference: Activity Code, Organization Codes and Definitions Used In Extramural Programs: http://grants.nih.gov/grants/funding/ac.pdf
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RESOURCE WEB LINKS  Office of Extramural Research Grants Home Page: http:// grants.nih.gov/grants/oer.htm  NIH Grants Policy Statement (12/03): http://grants.nih.gov/grants/policy/nihgps_2003/index.htm  NIH Guide: http://grants.nih.gov/grants/guide/index.html  PHS 398 Application (form pgs are PDF-fillable): http://grants1.nih.gov/grants/funding/phs398/phs398.html  PHS2590 Progress Report (form pgs are PDF-fillable): http://grants.nih.gov/grants/funding/2590/2590.htm  Handy Reference: Activity Code, Organization Codes and Definitions Used In Extramural Programs: http://grants.nih.gov/grants/funding/ac.pdf
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Getting Help • NIH Office of Extramural Research Human Subjects Website: http://grants.nih.gov/grants/policy/hs/ • Decision Chart for Research with Data/Specimens: http://www.hhs.gov/ohrp/humansubjects/guidance/45cfr46.htm#46.102 • OHRP Website: http://www.hhs.gov/ohrp/ • 45 CFR 46: http://www.hhs.gov/ohrp/humansubjects/guidance/45cfr46.htm • • SF 424 (Research & Related) & Electronic Submission Page http://grants.nih.gov/grants/funding/424/index.htm • PHS 398 Instructions: http://grants1.nih.gov/grants/funding/phs398/phs398.html • NIH Human Subjects Protection Education http://phrp.nihtraining.com/users/login.php • Inclusion: http://grants.nih.gov/grants/funding/women_min/women_min.htm 47 47
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Getting Help • NIH Office of Extramural Research Human Subjects Website: http://grants.nih.gov/grants/policy/hs/ • Decision Chart for Research with Data/Specimens: http://www.hhs.gov/ohrp/humansubjects/guidance/45cfr46.htm#46.102 • OHRP Website: http://www.hhs.gov/ohrp/ • 45 CFR 46: http://www.hhs.gov/ohrp/humansubjects/guidance/45cfr46.htm • • SF 424 (Research & Related) & Electronic Submission Page http://grants.nih.gov/grants/funding/424/index.htm • PHS 398 Instructions: http://grants1.nih.gov/grants/funding/phs398/phs398.html • NIH Human Subjects Protection Education http://phrp.nihtraining.com/users/login.php • Inclusion: http://grants.nih.gov/grants/funding/women_min/women_min.htm 58 58
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Federal Regulation Agencies Consumer ConsumerProduct Product Safety Commission Safety Commission http://www.cpsc.gov http://www.cpsc.gov Department Departmentof ofLabor Labor http://www.dol.gov http://www.dol.gov Environmental EnvironmentalProtection ProtectionAgency Agency http://www.epa.gov http://www.epa.gov Equal EqualEmployment Employment Opportunity OpportunityCommission Commission Federal FederalCommunications Communications Commission Commission 3.4 http://www.eeoc.gov http://www.eeoc.gov http://www.fcc.gov http://www.fcc.gov Federal FederalReserve ReserveSystem System http://www.federalreserve.gov http://www.federalreserve.gov Federal FederalTrade TradeCommission Commission http://www.ftc.gov http://www.ftc.gov Food Foodand andDrug DrugAdministration Administration http://www.fda.gov http://www.fda.gov National NationalLabor LaborRelations RelationsBoard Board http://www. http://www.nlrb.gov nlrb.gov Occupational OccupationalSafety Safetyand and Health Administration Health Administration Securities Securitiesand andExchange Exchange Commission Commission http://www.osha.gov http://www.osha.gov http://www.sec.gov http://www.sec.gov 22
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Funding Opportunities Sites with important information: http://grants.nih.gov/grants/index.cfm http://grants.nih.gov/grants/welcome.htm#introduction http://deainfo.nci.nih.gov/funding.htm http://deainfo.nci.nih.gov/extra/extdocs/grantrevprocess.htm http://www.niaid.nih.gov/ncn/grants/default.htm http://www.niaid.nih.gov/ncn/grants/charts/default.htm http://www.niaid.nih.gov/ncn/glossary/default.htm
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Producer Consumer Synchronized Circular Buffer Produced 1 into cell 0 write 1 read 0 buffer: Produced 2 into cell 1 write 2 read 0 buffer: Consumed 1 from cell 0 write 2 read 1 buffer: Produced 3 into cell 2 write 3 read 1 buffer: Produced 4 into cell 3 write 4 read 1 buffer: Produced 5 into cell 4 write 0 read 1 buffer: Produced 6 into cell 0 write 1 read 1 buffer: BUFFER FULL WAITING TO PRODUCE 7 Consumed 2 from cell 1 write 1 read 2 buffer: Produced 7 into cell 1 write 2 read 2 buffer: BUFFER FULL WAITING TO PRODUCE 8 Consumed 3 from cell 2 write 2 read 3 buffer: Produced 8 into cell 2 write 3 read 3 buffer: BUFFER FULL WAITING TO PRODUCE 9 Consumed 4 from cell 3 write 3 read 4 buffer: Produced 9 into cell 3 write 4 read 4 buffer: BUFFER FULL WAITING TO PRODUCE 10 Consumed 5 from cell 4 write 4 read 0 buffer: Produced 10 into cell 4 write 0 read 0 buffer: BUFFER FULL ProduceInteger finished producing values Terminating ProduceInteger 1 -1 -1 -1 -1 1 2 -1 -1 -1 1 2 -1 -1 -1 1 2 3 -1 -1 1 2 3 4 -1 1 2 3 4 5 6 2 3 4 5 Consumed 6 from cell 0 write 0 read 1 buffer: Consumed 7 from cell 1 write 0 read 2 buffer: Consumed 8 from cell 2 write 0 read 3 buffer: Consumed 9 from cell 3 write 0 read 4 buffer: Consumed 10 from cell 4 write 0 read 0 buffer: BUFFER EMPTY ConsumeInteger retrieved values totaling: 55 Terminating ConsumeInteger 6 6 6 6 6 6 2 3 4 5 6 7 3 4 5 6 7 3 4 5 6 7 8 4 5 6 7 8 4 5 6 7 8 9 5 6 7 8 9 5 6 7 8 9 10 7 7 7 7 7 8 8 8 8 8 9 9 9 9 9 10 10 10 10 10 Ref: http://userhome.brooklyn.cuny.edu/irudowdky/OperatingSystems.htm & Silberschatz, Gagne, & Galvin, Operating Systems Concepts, 7th ed, Wiley (ch 1-3)
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Other Resources • NIH Training Website: • http://grants.nih.gov/training/nrsa.htm#policy • T Kiosk (FOAs): http://grants.nih.gov/training/T_Table.htm • F Kiosk (FOAs): http://grants.nih.gov/training/F_files_nrsa.htm • Fellowship Application Guide: http://grants1.nih.gov/grants/funding/424/index.htm • Training Grant Instructions: See Section 8 of the SF424 (R&R) Application Guide: http://grants.nih.gov/grants/funding/424/index.htm 68
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Resources • About the Public Access Policy: – http://publicaccess.nih.gov/ – NIH Guide Notice for Public Access (January 2008): http://grants.nih.gov/grants/guide/notice-files/NOT-OD-08-033.html – New Guide Notice for Grantee Compliance (September 2008): http://grants.nih.gov/grants/guide/notice-files/NOT-OD-08-119.html – Email Questions: [email protected] • The NIH Manuscript Submission System: – http://www.nihms.nih.gov/ – Tutorials: http://www.nihms.nih.gov/web-help/ • PubMed Central: – http://www.pubmedcentral.nih.gov/ – Educational Video: http://www.ncbi.nlm.nih.gov/Education/pmc/ – Information for Publishers: http://www.pubmedcentral.nih.gov/about/pubinfo.html 18
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